What is FLT3-positive AML? What is gilteritinib? #AML from flt3 itd mutation positive Watch Video

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HealthTree University for Blood Cancers

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Presented by Mark J. Levis, MD, PhD nnDr. Levis presents results of the QuANTUM-R trial, the first positive phase 3 trial to demonstrate improved OS with single-agent quizartinib in the R/R FLT3-ITD AML setting compared with salvage chemotherapy. The data confirm the safety and efficacy of quizartinib and the value of targeting the FLT3-ITD driver mutation with a highly potent and selective FLT3 inhibitor.
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Research suggests that a new targeted therapy, quizartinib, may be a safe and effective option to treat a subset of patients with treatment-resistant acute myeloid leukaemia (AML), whose leukaemia has the FLT3-ITD mutation.nnQuizartinib is the first and only single-agent drug that has produced a clinical benefit in AML patients with this deadly mutation who have failed previous therapy.nnThe number of patients bridged to a stem cell transplant was very significant. Dr Levis and his colleagues pl
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