_dr-romain-yvinec-kinetic-biased-signaling-towards-a-system-biology-definition-of-drugs-selectivity-illustration-on-th.jpg "Dr Romain Yvinec - Kinetic biased signaling: towards a system biology definition of drugs selectivity. Illustration on the... from selectivity definition drugs Video Screenshot Preview")
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⏲ Duration: 8 min 5 sec
✓ Published: 03-Oct-2022
✓ Published: 03-Oct-2022
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Dr Romain Yvinec, Physiology of Reproduction and Behaviour (PRC) / Centre INRAE Val de Loire, CNRS, University of Tours, IFCEnnnnAn active area of research in pharmacology and drug discovery applies to functional selectivity: the ability of a ligand to selectively activate some signal transduction pathways as compared to the native ligand acting at the same receptor. nAt the theoretical level, biased signaling is supported by the concept of conformational selectivity: a given receptor may adopt
Dr Romain Yvinec, Physiology of Reproduction and Behaviour (PRC) / Centre INRAE Val de Loire, CNRS, University of Tours, IFCEnnnnAn active area of research in pharmacology and drug discovery applies to functional selectivity: the ability of a ligand to selectively activate some signal transduction pathways as compared to the native ligand acting at the same receptor. nAt the theoretical level, biased signaling is supported by the concept of conformational selectivity: a given receptor may adopt
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